Description
The popular SARM, LGD-4033, is known by various names in the scientific community, including Ligandrol, VK5211, and Anabolicum. Researchers have found that Ligandrol is effective in creating lean muscle mass and treating bone conditions such as osteoporosis. In one study involving 76 healthy men, most participants reported that LGD-4033 was well-tolerated. Current studies indicate that VK5211 does not exhibit anabolic steroid effects, and it has the potential to increase stamina and promote libido.
High-Quality LGD 4033 For Sale
LGD 4033, also known as Ligandrol, is a selective androgen receptor modulator (SARM) that can provide the benefits of anabolic steroids without the associated negative side effects. It promotes an increase in lean muscle mass, enhances libido, and improves stamina. LGD 4033 is not only effective on its own but is also one of the easiest SARMs to stack. This high-quality product is available from Sarmsamerica in a bottle containing 60 capsules, each with 10 mg of Ligandrol. Taken orally, this tissue-selective SARM can positively impact muscle weakness caused by osteoporosis, cancer, and aging.
What Is LGD 4033 Ligandrol?
LGD-4033 is a third-generation non-steroidal oral SARM with a high affinity for the androgen receptor (Ki of ~1 nM). It is currently the second most popular SARM on the market. Unlike testosterone, which exerts anabolic effects through the same pathway, LGD-4033 has high selectivity for receptors in skeletal muscle, bone, and connective tissue, with minimal affinity for receptors in the prostate, scalp, and skin.
LGD-4033, developed by Ligand Pharmaceuticals, aims to treat conditions such as muscle wasting and osteoporosis without the virilizing side effects of anabolic steroids. Many researchers consider LGD-4033 to be the best SARM for producing lean body mass. Sarmsamerica is the best place to buy LGD-4033 online.
LGD 4033 and Muscle Mass
Preclinical primate data showed a significant dose-dependent increase in lean body mass for male and female monkeys over 13 weeks at doses of 0.6, 3, 15, or 75 mg/kg of body weight. Notably, 70% of the increased body mass was retained after a 4-week recovery period.
Only the 75 mg/kg group discontinued testing after 48 days due to toxicity. This dosage is significantly higher than the highest quantity administered in clinical trials.
LGD 4033 and Bone Recovery
A Phase 1 clinical trial involving 76 adult males who were orally administered LGD-4033 in varying quantities showed a dose-dependent increase in lean body mass and was well tolerated by all participants over 21 days. In Phase 2 clinical trials, 120 subjects recovering from hip fracture surgery received either a placebo or 0.5, 1, or 2mg of LGD-4033 over 12 weeks.
All doses of LGD-4033 resulted in significant increases in total lean body mass, with subjects showing dose-dependent decreases in mean fat mass.
Subjects administered LGD-4033 showed improvements in serum procollagen type 1 propeptide (s-P1NP), a marker of bone anabolism, and improvements in the 6-minute walk distance compared to the placebo group. No significant adverse effects were reported in any of the study groups.
Subjects were assessed 12 weeks after the completion of the trial, and they maintained the muscle mass they had gained from the compound.
Potential Research Findings
- Lean Muscle Development:
- LGD-4033 has been studied for its ability to promote increases in lean muscle mass by activating androgen receptors in skeletal muscle.
- Strength Enhancement:
- Research suggests LGD-4033 may improve strength and power, supporting muscle performance under experimental conditions.
- Endurance Support:
- Some studies indicate its potential to enhance stamina and physical endurance, aiding in prolonged physical activity during research trials.
- Fat Mass Reduction:
- Findings suggest LGD-4033 may assist in reducing fat mass while preserving lean tissue, making it a focus of studies related to metabolic health.
- Bone Health:
- LGD-4033 has shown promise in improving bone density and strength by targeting androgen receptors in muscle and bone tissues, potentially useful for conditions like osteoporosis.
- Accelerated Recovery:
- Experimental studies highlight its potential to shorten recovery times, reducing muscle soreness and fatigue after strenuous activity.
- Reduced Adverse Effects:
- Compared to anabolic steroids, LGD-4033 has demonstrated fewer side effects in research settings, though long-term studies are ongoing.
- Minimal Androgenic Impact:
- Preclinical findings suggest LGD-4033 does not significantly cause androgenic effects, such as hair loss or prostate enlargement, making it selective in its tissue targeting.
- Convenient Administration:
- LGD-4033 is typically administered orally in research models, making it a convenient compound for experimental protocols.
Proper Amount for LGD 4033 Ligandrol
For LGD 4033, studies made for research purposes said a common dose for men ranges between 5mg and 10mg per day on a six-week cycle. For women, the recommended dose was between 2.5mg and 5mg per day for the same period.
Due to its potency, it’s important to implement a post-cycle therapy (PCT) after completing a cycle. Additionally, a six-week break should be taken before starting a new cycle with Ligandrol.
The Stackability of LGD 4033 Ligandrol
Numerous stacks can be created with LGD 4033 (Ligandrol), yielding impressive results within the stack’s duration. The most popular combination of Ligandrol, Ostarine, and Cardarine is detailed below, including the recommended cycle length and dosages for optimal benefits.
Each of these SARMs offers unique benefits. For instance, Ostarine has a similar effect to LGD 4033 in promoting lean muscle mass. However, Ostarine’s half-life is only 24 hours, while Ligandrol’s half-life ranges from 24 to 36 hours, making it slightly more potent.
Cardarine enhances the benefits of Ostarine and Ligandrol by boosting various areas. One major advantage of Cardarine is its ability to burn fat even while at rest. Additionally, it improves endurance for longer workouts, reduces inflammation for quicker recovery, and helps prevent plaque buildup in arteries.
When it comes to stacking, the traditional doses for men using these three together are straightforward. LGD 4033 is taken at 10mg per day throughout the stack. For women, the recommended dose is around 5mg per day of Ligandrol. Both Ostarine and Cardarine are set at 20mg per day for men, while women should take 10mg per day of each. A typical cycle length for this stack is about six weeks.
Data on our LGD 4033 for sale
CAS Number: |
1165910-22-4 |
Formula: |
C14H12F6N2O |
Molar Mass: |
338.258 g/mol |
Half-life: |
24 – 36 hours |
Class: |
Selective Androgen Receptor Modulator |
Storage: |
Store in a cool dry place away from direct sunlight to maximize shelf life.
|
LGD 4033 (Liquid Ligandrol) FAQs
What is LGD-4033 best for?
LGD-4033 enhances bone density through the activation of androgen receptors in muscle tissue, leading to increased bone density and strength. Additionally, LGD-4033 can elevate red blood cell count by boosting protein synthesis, which contributes to improved bone density and lean muscle mass.
Is LGD-4033 better for bulking or cutting?
Ligandrol is considered to be 11x stronger than ostarine, helping you gain muscle and size in a short amount of time. The perfect step up for anyone on a massing phase.
Is LGD4033 the strongest SARM?
Yes, LGD4033 is the strongest SARM when evaluated on a per milligram basis.
Can LGD4033 trigger gynecomastia?
To date, there are no studies suggesting that gynecomastia results from LGD4033 administration.
Can LGD4033 suppress testosterone?
Yes, LGD4033 can suppress natural testosterone levels in male test subjects.
How long does LGD take to work?
In a Phase 1 clinical trial involving 76 healthy young men, a daily dose of 1 mg of LGD-4033 increased lean body mass by 1.2 kg after 3 weeks of treatment.
Why is Sarmsamerica the best place to buy Ligandrol online?
Based on the above information, it’s easy to understand why many researchers consider LGD 4033 to be the best SARM for adding lean mass to a test subject.
If you’re looking to buy Ligandrol online, you’ll find plenty of options. However, Sarmsamerica stands out as the best place to buy LGD 4033 online due to its consistent, verifiable high-quality products, safe bottling and packaging, fast shipping, and excellent customer service. Additionally, our LGD-4033 is available in SARM Stack.
When you buy SARMs from Sarmsamerica, you are choosing the highest quality ingredients. Our compounds are a minimum of 98% pure, tested and certified by accredited American third-party labs and suspended in USP grade PEG400, the highest grade available, all bottled in America.
We run a transparent business with no discreet payment methods needed and no misrepresentation of our products. We offer only the highest quality research chemicals available online. Enjoy free shipping on orders over $160, and if you need your products quickly, we offer express shipping as well. Plus, customers who sign up for our email list receive a 10% discount.
When you choose Sarmsamerica, you are selecting the highest quality LGD-4033 available anywhere on the internet. Our products often exceed the quality of the reference samples they are tested against.
That’s why we are confident in our claim that we offer the best Ligandrol for sale on the market today. Browse our list of SARMs for sale, and if you have any questions about our Ligandrol, you can contact us, and we’ll respond as soon as possible.
Abuse Warning
LGD 4033 is an investigational compound still awaiting FDA approval and is not a dietary supplement. At Sarmsamerica, we are chemical suppliers, not medical doctors, and our expertise lies in sourcing and quality control. Sarmsamerica does not encourage or condone consumer use of SARM products; they are intended for research purposes only.
SARMs should only be used under the supervision and direction of a medical doctor or designated research authority. We strongly discourage the use of SARMs for performance enhancement in sports and bodybuilding. We warn against relying on “bro science” and peer consensus when making decisions about human health, as these products are not for human consumption and should only be utilized by researchers or in clinical trials.
Scientific References:
- Basaria et al. The Safety, Pharmacokinetics, and Effects of LGD-4033, a Novel Nonsteroidal Oral, Selective Androgen Receptor Modulator, in Healthy Young Men. The Journals of Gerontology: Series A, Volume 68, Issue 1, January 2013, Pages 87–95.
- Fragkaki et al. Human in vivo metabolism study of LGD-4033. Drug Test Analysis. Drug Test Anal. 2018 Nov;10(11-12):1635-1645. doi: 10.1002/dta.2512. Epub 2018 Nov
- Fragkaki, A.G., Sakellariou, P., Kiousi, P., Kioukia-Fougia, N., Tsivou, M., Petrou, M. and Angelis, Y. (2020), Human in vivo metabolism study of LGD-4033. Drug Test Analysis,12: 164-164.
- “Viking Therapeutics Initiates Phase 2 Trial of VK5211 in Patients Recovering From Hip Fracture.” FierceBiotech.Questex LLC, 03 Nov. 2015. Web. 21 Nov. 2016.
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111291/
- https://www.frontiersin.org/articles/10.3389/fendo.2020.556581/full
- https://pubchem.ncbi.nlm.nih.gov/compound/44137686
*Disclaimer: These products are not intended to diagnose, treat, or cure any condition or disease.