Description
Epitalon, also called Epithalon, is a synthetic polypeptide composed of four amino acids. It is derived from epithalamin and works by activating the natural production of the telomerase enzyme, as well as stimulating melatonin release from the pineal gland. The Epitalon Peptide is a synthetic version of the naturally occurring Epithalamin and is available in 10 mg vials from Sarmsamerica.
What Is Epitalon?
Epitalon is the synthetic version of what researchers call epithalamin. Animal studies on Epitalon have demonstrated its potential to treat liver disorders, geriatric conditions, as well as psychiatric and neuropathological issues.
Epithalamin Peptide contributes to regulating cell replication and the anterior pituitary gland in vivo. Epitalon was discovered by Russian doctor and Peptide engineer Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology and has been studied for over 35 years.
Epitalon is highly valued by anti-aging experts and is considered a potential fountain of youth. Studies in mice and rats have demonstrated that Epitalon can improve age-related diseases, enhance skin health and appearance, increase resistance to emotional stress, stimulate the production of new cells, rejuvenate muscle cells, and extend lifespan by delaying age-related changes in the reproductive and immune systems.
This effect may be more pronounced in individuals with naturally shorter telomeres. Preliminary studies have shown significant impacts of Epitalon treatment on certain types of cancerous cells, infections, and DNA regulation.
Epitalon and DNA Protection
Epitalon Peptide has demonstrated antioxidant activity in the body by helping to eliminate free radicals. Experimental evidence on somatic cells indicates that Epitalon treatment activates the enzyme telomerase and stimulates its natural production.
Telomere shortening is associated with aging, and telomerase is among several naturally occurring components regarded as potential fountains of youth. This is because telomerase may stimulate the production of new cells and rejuvenate existing ones.
Activation of the telomerase enzyme directly enhances cell health, lengthens telomeres, reduces DNA strand errors, and protects chromosomes and DNA from damage.
Research indicates that Epitalon directly interacts with DNA to enhance the expression of specific genes, including CD5, IL-2, MMP2, and Tram1, as well as promoting the natural production of telomerase.
Anti-Tumor Effects of Epithalon
In rats, Epitalon has been shown to improve muscle cell health and reduce tumor growth. Treatment with synthetic Epitalon Peptide not only decreased tumor growth but also prevented metastasis (the spread of cancer). Consequently, Epitalon is currently being investigated as a potential treatment for Her-2/neu positive breast cancers, leukemia, and testicular cancer.
Epitalon and Sleep Quality
Studies on rats have shown that Epitalon and related Peptides influence circadian rhythm by affecting the creation and release of melatonin. This is achieved through their impact on two proteins: pCREB transcription protein and arylalkylamine-N-acetyltransferase (AANAT).
These two proteins are essential for the regular production and day/night release of melatonin from the pineal gland. Research involving monkeys suggests that Epitalon Peptide therapy can normalize melatonin release.
Enhancing circadian regularity and achieving deeper sleep are known to improve skin health and appearance, stimulate the production of new muscle cells, regulate the anterior pituitary gland, increase cell replication, and boost resistance to emotional stress and age-related diseases.
Deep, restorative sleep is considered by many health experts as the natural fountain of youth, essential for muscle cell health, the production of new cells, and life extension.
Epitalon Effects on Spontaneous Carcinogenesis: Female C3H/He Mice Model
The study explored the potential preventive effects of the synthetic pineal Peptide Epitalon (Ala-Glu-Asp-Gly) on spontaneous tumorigenesis in mice. One-year-old female C3H/He mice were kept under standard conditions for 6.5 months, during which they received Epitalon injections five times a week. Long-term exposure to small doses of Epitalon showed no toxic effects.
Treatment with Epitalon significantly reduced the number of mice bearing malignant tumors and effectively prevented the development of metastases. The predominant spontaneous tumors were located in the reproductive organs, particularly the mammary glands and ovaries. Mammary gland tumors mainly consisted of various forms of invasive ductal carcinomas, while granulosa-cell tumors were observed in the ovaries. Tumors in other organs were less common and generally benign. [2]
In the control group, metastases were detected in 3 out of 9 tumor-bearing mice, all originating from reproductive organ tumors. Conversely, Epitalon treatment significantly slowed metastatic development from spontaneous tumors, with no metastases found in the experimental mice. These findings emphasize the antimetastatic effect of Epitalon, highlighting its oncostatic properties.
Treatment on Rats for Eye Retina Condition in Retinitis Pigmentosa
The study investigated the effects of the tetrapeptide Epitalon (Ala-Glu-Asp-Gly) on congenital pigmented degeneration of the retina. Experiments conducted on Campbell rats revealed that Epitalon application enhanced both the bioelectric and functional activity of the retina, primarily by preserving its morphological structure. These findings suggest that Epitalon may play a crucial role in maintaining retinal health and functionality.
Moreover, clinical trials involving patients with degenerative retinal lesions revealed promising results with Epitalon therapy, showing a positive clinical effect in 90% of cases. These findings underscore the potential therapeutic value of Epitalon in treating retinal degenerative disorders in humans. [3]
Further analysis of Epitalon’s effects indicates its involvement in common transcription mechanisms shared by the pineal gland and the retina. This underscores the complex interplay between Epitalon and the key molecular pathways that regulate cellular function and homeostasis in both the pineal gland and the retina. [3]
Overall, the study highlights the potential therapeutic benefits of Epitalon in preserving retinal health and function. It provides insights into its mechanisms of action and broader implications for treating retinal degenerative conditions. [3]
Epitalon Side Effects
Aside from potential injection site inflammation, Epitalon therapy has not shown significant side effects in human and animal studies. However, this does not guarantee the safety of using Epitalon Peptide. Long-term clinical trials are necessary to confirm its safety, potential side effects, clinical significance, and relative efficacy.
Data on our Epitalon for sale
| CAS Number: | 307297-40-1 |
| Formula: | C14H22N4O9 |
| Sequence: | Ala-Glu-Asp-Gly |
| Molar Mass: | 390.35 g/mol |
| Class: | Tetrapeptide |
| Storage: | Keep refrigerated upon reconstitution.
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What is the Function of Epitalon?
The primary function of Epitalon is to boost the production of telomerase, a natural enzyme that safeguards and restores telomeres. This process promotes DNA replication and the generation of new cells.
Does Epitalon Build Muscle?
Epitalon interacts with the pineal gland in the brain to promote the formation of new cells and may enhance muscle mass and bone density.
Does Epitalon Increase Testosterone?
Epitalon has been shown to restore reproductive function in older rats, reestablishing the female estrus cycle and increasing male plasma testosterone levels by 30%.
What Is the Epthalamin Hormone?
Epithalamin has been shown to stimulate melatonin production in elderly adults with pineal gland dysfunction (Korkushko et al., 2004) and in older rats (Anisimov et al., 1992). However, preclinical evidence regarding the synthetic Epitalon’s ability to produce similar effects remains conflicting.
Why Buy Epitalon 10mg from Sarmsamerica?
If you’re looking to buy Epithalon, finding a seller is easy, but Sarmsamerica is the best place to buy Epitalon online. They offer consistent, verifiable high-quality products, fast shipping, and excellent customer service.
A quick search will reveal many websites offering Epitalon for sale. However, not all of these companies are trustworthy, and in many cases, you can’t be certain of the product’s quality when buying Peptides from them, especially if they lack third-party certifications.
At Sarmsamerica, you can buy the highest quality Epitalon with confidence, as every batch is third-party tested and certified by an accredited US-based laboratory. When you buy Peptides from Sarmsamerica, you are selecting the highest quality products. Our Peptides are lyophilized in glass bottles and stored in refrigeration to prevent degradation.
Our research chemicals are lyophilized in glass vials and stored refrigerated to maintain potency. We operate a transparent business, avoiding discreet payment methods and ensuring no misrepresentation of our products. Explore the highest quality online.
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If you want to learn more about our Epitalon for sale for laboratory research use, please don’t hesitate to contact us.
Research:
[1]Â https://pubmed.ncbi.nlm.nih.gov/14647006/
[2]Â https://pubmed.ncbi.nlm.nih.gov/16634527/
[3]Â https://pubmed.ncbi.nlm.nih.gov/12195242/
Disclaimer: The Epitalon currently listed on this site is sold for research use only and is not intended for human consumption. This product is not a compound, supplement, food, or cosmetic, and should not be misused, sold, labeled, or branded as such. These products are not intended to diagnose, treat, or cure any condition or disease and are strictly for research purposes only.
