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DSIP 5mg

Original price was: $49.95.Current price is: $39.95.

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Description

DSIP 5mg (Delta Sleep Inducing Peptide)

Sarmsamerica offers DSIP peptide for sale, manufactured to the highest quality and potency standards. Naturally occurring DSIP has been found in several brain areas, including the pituitary gland and hypothalamus, two major regulators. It is also present in the adrenal glands. Primary studies on DSIP focus on its effects on sleep patterns, motor activity, and delta EEG activity. Users of DSIP peptide have reported improvements in sleep regulation, normalized blood pressure, and stimulated LH release.

High Quality DSIP for sale (Delta Sleep-Inducing Peptide)

Delta sleep-inducing peptide (DSIP) is a nine-amino acid peptide involved in various physiological and endocrine functions. It has been linked to altering corticotropin levels, improving sleep patterns, normalizing blood pressure, inhibiting somatostatin secretion, reducing stress, and diminishing pain perception. Additionally, DSIP may have potential applications in preventing free radical damage, cancer treatment, and managing depression.

Role of DSIP in Sleep Regulation

Sleep-Wake Cycle Regulation

DSIP was initially isolated from rabbit brains during slow-wave sleep and has been linked to the regulation of sleep-wake cycles in the central nervous system. While the synthesis and specific location of DSIP within the body remain unknown, studies have found that DSIP levels are equally high in external tissues and the central nervous system. This suggests that DSIP’s primary function may extend beyond sleep and that it may be produced outside the central nervous system. Animal models indicate that DSIP regulates heart rate, blood pressure, thermogenesis, and the lymphokine system, potentially preparing the body for sleep by altering its physiology.

Promotion of Sleep

While research on the mechanism underlying the connection between DSIP and sleep patterns remains conflicting, it is evident that DSIP is related to the onset of sleep. Human studies have shown that DSIP promotes sleep by inducing feelings of sleepiness, shortening sleep onset, and increasing total sleep time by 59% compared to a placebo. However, electroencephalogram (EEG) recordings do not demonstrate sedation, presenting a paradoxical finding. Notably, a significant research study demonstrated that DSIP improved sleep to match that of control subjects in individuals with chronic insomnia. Studies utilizing polysomnographic equipment have revealed that DSIP enhances sleep efficiency.

DSIP 5mg (Delta Sleep Inducing Peptide)

DSIP Molecule

 

Potential of DSIP Beyond Sleep Regulation

DSIP is thought to be a hypothalamic hormone with the potential to regulate more than just sleep, similar to how growth hormone influences various physiological aspects beyond bone and muscle growth. Studies have shown that DSIP restricts the production of somatostatin, a protein produced in muscle cells that inhibits muscle growth. Like GHRP6, DSIP increases growth hormone activity, promoting muscle growth and enlargement. These findings have led researchers to hypothesize that DSIP may have a broader regulatory role in human physiology, extending beyond sleep promotion.

DSIP and Pain Perception and Relief

Research in rats suggests that DSIP may activate opioid receptors, resulting in a dose-dependent reduction in pain sensations. While opioids and DSIP act on the same receptors in the central nervous system (CNS), DSIP does not induce the same level of dependency associated with opioid medications. A preclinical trial in humans demonstrated that DSIP significantly reduced pain perception and improved mood. Additionally, DSIP exhibited the ability to mitigate pain rebound and other withdrawal symptoms often occurring after discontinuing long-term pain therapy, indicating its potential usefulness for patients who are physiologically dependent on other pain medications.

DSIP Potential in Cancer Prevention

Research in rats suggests that DSIP may activate opioid receptors, resulting in a dose-dependent reduction in pain sensations. While opioids and DSIP act on the same receptors in the central nervous system (CNS), DSIP does not induce the same level of dependency associated with opioid medications. A preclinical trial in humans demonstrated that DSIP significantly reduced pain perception and improved mood. Additionally, DSIP exhibited the ability to mitigate pain rebound and other withdrawal symptoms often occurring after discontinuing long-term pain therapy, indicating its potential usefulness for patients who are physiologically dependent on other pain medications.

Data on our DSIP for sale

CAS Number: 62568-57-4

Formula: C35H48N10O15

Sequence: N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C

Molar Mass:  848.81 g/mol

Class: Neuropeptide

Storage: Keep refrigerated upon reconstitution.

  • Lyophilized sample in sterile glass vial.
  • Minimum 98% pure.
  • 5mg DSIP peptide per vial.
  • Diluent and laboratory supplies not included.

DSIP FAQs

How does DSIP work?

DSIP plays a role in the regulation of circadian rhythm. It also influences the secretion of adrenocorticotropic hormone (ACTH), luteinizing hormone (LH), and Growth Hormone.

Is Delta sleep good for you?

Delta sleep has been shown to improve both physical health and cognitive function. Delta brainwaves are associated with enhanced memory, extended attention span, and quicker reaction time.

What are the side effects of DSIP?

At higher doses, DSIP has been reported to cause side effects such as headaches, nausea, dizziness, and fatigue.

Why buy DSIP peptide from Sarms America?

If you’re looking to buy DSIP peptide, there are many options available. However, purchasing Delta Sleep Inducing Peptide from a randomly selected company can be risky. Many peptide vendors do not test their products or hide their certificates and contact information for their third-party labs from customers. What might they be hiding?

At Sarmsamerica, you can find the best peptides for sale online. When you buy peptides from Sarmsamerica, you are choosing the highest quality ingredients.

Our pure compounds are tested and certified by accredited American third-party labs, which accept phone calls to verify the validity of their certificates. Our products are lyophilized in glass bottles and stored under refrigeration to prevent degradation. We operate a transparent business with no discreet payment methods and no misrepresentation of our products, offering only the highest quality research chemicals available online, backed by our 60-day money-back guarantee.

For order over $160, we offer free shipping. Need your items fast? We also provide express shipping services. Plus, sign up for our newsletter to get a 10% discount.

Sarmsamerica is the premier destination to buy DSIP online, thanks to our consistent, verifiable high-quality products, secure bottling and packaging, fast shipping, and excellent customer service. We are confident that we offer the best DSIP for sale on the market today. If you have any questions about our DSIP or other products, feel free to contact us, and we will respond as soon as possible.

References:

  1. Yehuda S, Carasso RL. DSIP–a tool for investigating the sleep onset mechanism: a review. Int J Neurosci. 1988 Feb;38(3-4):345-53. doi: 10.3109/00207458808990695. PMID: 3286557.
  2. Schneider-Helmert D, Gnirss F, Monnier M, Schenker J, Schoenenberger GA. Acute and delayed effects of DSIP (delta sleep-inducing peptide) on human sleep behavior. Int J Clin Pharmacol Ther Toxicol. 1981 Aug;19(8):341-5. PMID: 6895513.
  3. Schneider-Helmert D. Effects of delta-sleep-inducing peptide on 24-hour sleep-wake behaviour in severe chronic insomnia. Eur Neurol.1987;27(2):120-9. doi: 10.1159/000116143. PMID: 3622582.
  4. Bes F, Hofman W, Schuur J, Van Boxtel C. Effects of delta sleep-inducing peptide on sleep of chronic insomniac patients. A double-blind study. Neuropsychobiology.1992;26(4):193-7. doi: 10.1159/000118919. PMID: 1299794.
  5. Koval’zon VM. DSIP: peptid sna ili neizvestnyĭ gormon gipotalamusa [DSIP: the sleep peptide or an unknown hypothalamic hormone?]. Zh Evol Biokhim Fiziol.1994 Mar-Apr;30(2):310-9. Russian. PMID: 7817664.
  6. Nakamura A, Nakashima M, Sugao T, Kanemoto H, Fukumura Y, Shiomi H. Potent antinociceptive effect of centrally administered delta-sleep-inducing peptide (DSIP). Eur J Pharmacol.1988 Oct 18;155(3):247-53. doi: 10.1016/0014-2999(88)90510-9. PMID: 2853064.
  7. Larbig W, Gerber WD, Kluck M, Schoenenberger GA. Therapeutic effects of delta-sleep-inducing peptide (DSIP) in patients with chronic, pronounced pain episodes. A clinical pilot study. Eur Neurol.1984;23(5):372-85. doi: 10.1159/000115716. PMID: 6548970.
  8. Popovich IG, Voitenkov BO, Anisimov VN, Ivanov VT, Mikhaleva II, Zabezhinski MA, Alimova IN, Baturin DA, Zavarzina NY, Rosenfeld SV, Semenchenko AV, Yashin AI. Effect of delta-sleep inducing peptide-containing preparation Deltaran on biomarkers of aging, life span and spontaneous tumor incidence in female SHR mice. Mech Ageing Dev. 2003 Jun;124(6):721-31. doi: 10.1016/s0047-6374(03)00082-4. PMID: 12782416.
  9. DSIP Peptide: Exploring its Potential in Sleep Regulation and Stress Management. Peptide Information(2023).

Disclaimer: The DSIP Peptide listed on this site is sold for research use only and is not intended for human consumption. This product is not a drug, supplement, food, or cosmetic, and should not be misused, sold, labeled, or branded as such. These products are not intended to diagnose, treat, or cure any condition or disease. They are strictly for research purposes only.