Description
Sarmsamerica offers GHK-Cu for sale at the highest quality and potency. Research indicates that GHK-Cu stimulates blood vessels and nerve outgrowth. Recent studies also show that GHK-Cu can protect skin cells from harmful UV rays and reduce inflammation.
Introduction to GHK-Cu
GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine, investigated for its potential therapeutic benefits in various studies and trials. Found naturally in human blood, urine, and saliva, GHK-Cu positively affects wound healing and skin regeneration. The Peptide attracts fibroblasts and immune cells to injured areas, promoting the repair of damaged tissues.
The Role of GHK-cu in Skin Regeneration and Age-Related Research
Stimulation of Collagen Synthesis
Copper Peptide GHK-Cu is a small molecule known for targeting inflammation and oxidative stress. Studies suggest that copper Peptides may also play a significant role in skin repair processes.
It does this by stimulating the synthesis of collagen, a key component of the skin’s structure. This stimulation leads to the reduction of scars and improvement in skin texture. It is also capable of the repair of aging skin. It does this by enhancing the elasticity, tightening, and firming the skin, making it a common ingredient in skincare and cosmetic products.
Reduction of Sun Damage and Wrinkles
Scientific investigations have clearly demonstrated that GHK-Cu can mitigate the adverse effects of sun exposure while enhancing the appearance of fine lines and wrinkles. These regenerative properties result in smoother skin with a more youthful and revitalized appearance.
GHK-cu Copper Molecule
Promotion of Blood Vessel Growth
An adequate blood supply is crucial for wound healing and tissue repair. GHK-Cu has shown the ability to promote blood vessel growth, supporting these essential processes.
Research of GHK Cu Antimicrobial and Wound Healing Effects
Antimicrobial Properties of GHK Cu
When combined with fatty acids, GHK-Cu transforms into an antimicrobial compound capable of fighting off various bacteria and fungi. This combination aids in wound healing by addressing potential pathogens that could hinder the healing process.
Further Wound Healing Enhancement
This technique was also studied in diabetic patients with ulcers, where GHK-Cu helped in healing and reducing the risk of infections. Similar results were observed in patients with open wounds and local blood supply deficiencies.
Pain Relief Research of GHK-Cu
Increase in L-Lysine Levels
Research on rats has shown that GHK-Cu can elevate levels of L-lysine, a natural painkiller in the body. By boosting L-lysine levels, GHK-Cu may possess pain-relieving properties.
Increase in L-Arginine Levels
L-arginine is another painkilling amino acid that enhances nitric oxide synthesis and blood flow. GHK-Cu increases L-arginine levels, further contributing to the Peptide’s potential for pain relief.
GHK cu Neuroprotective and Anti-Degenerative Effects
Research suggests that GHK-Cu plays a protective role in the nervous system, particularly in the brain, where it is found in high concentrations. Aging is associated with a decline in GHK-Cu levels, which may contribute to neurodegeneration.
GHK-Cu has been found to increase nerve outgrowth, reduce inflammation, and enhance blood vessel development in the central nervous system. It shows potential in combating the decline in neurological function associated with degenerative diseases like Alzheimer’s and has demonstrated the ability to reset pathological gene expression.
GHK-Cu Mitigates LPS-Induced Lung Injury in Mice
This study, conducted on mice, explores the potential of the tripeptide-copper complex glycyl-l-histidyl-l-lysine-Cu (II) (GHK-Cu) in managing acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). GHK-Cu treatment exhibits significant protective effects in lipopolysaccharide (LPS)-induced RAW 264.7 macrophages in vitro and in ALI in mice in vivo.
The treatment modulates reactive oxygen species (ROS) production, enhances superoxide dismutase (SOD) activity, and reduces TNF-α and IL-6 production by suppressing the NF-κB p65 and p38 MAPK signaling pathways. In vivo, GHK-Cu alleviates LPS-induced lung histological alterations and reduces the infiltration of inflammatory cells into the lung parenchyma. These findings suggest that GHK-Cu is a promising therapeutic option for ALI/ARDS by moderating excessive inflammatory responses.
GHK-Cu Reduces Bleomycin-Induced Lung Fibrosis in Animals
This study investigates the therapeutic efficacy of the tripeptide-copper complex glycyl-L-histidyl-L-lysine (GHK-Cu) in a mouse model of bleomycin (BLM)-induced pulmonary fibrosis. BLM-induced pulmonary fibrosis, characterized by progressive diffuse fibrosis, oxidative stress, and inflammation, is mitigated with intraperitoneal injections of GHK-Cu at various dosages.
GHK-Cu demonstrates a protective effect by inhibiting BLM-induced inflammatory and fibrotic changes, reducing inflammatory cytokines, and ameliorating collagen deposition. Additionally, it corrects the MMP-9/TIMP-1 imbalance, partially prevents epithelial-mesenchymal transition (EMT) through the Nrf2, NF-κB, and TGFβ1 pathways, and inhibits Smad2/3 phosphorylation. These findings highlight GHK-Cu’s potential in preventing BLM-induced inflammation and oxidative stress, hindering EMT progression, and suppressing TGFβ1/Smad2/3 signaling in pulmonary fibrosis.
Data on our GHK-cu for Sale
| CAS Number: |
89030-95-5 |
| Formula: |
C14H22CuN6O4 |
| Sequence: |
(GLY-HIS-LYS)-Cu-HAc |
| Molar Mass: |
340.38 g/mol |
| Class: |
Tripeptide |
| Storage: |
Keep refrigerated upon reconstitution.
|
FAQs About the GHK-Cu Peptide
What Is GHK Cu Used for?
GHK-Cu is a copper Peptide with clinical significance in improving skin firmness and elasticity by promoting collagen formation. It may also reduce hyperpigmentation and skin spots, though further research is needed in this area.
What to Avoid When Using Copper Peptides?
When conducting research with GHK-Cu, it is advisable to avoid using retinol, vitamin C, and alpha hydroxy acids (AHAs) like glycolic acid in a chemical peel.
Do Copper Peptides Regrow Hair?
Copper Peptides like GHK-Cu may promote new hair growth and improve the health of existing hair follicles due to their anti-inflammatory properties.
What Are the Side Effects of GHK-Cu?
Reported side effects of GHK-Cu include nausea, headaches, fatigue, changes in blood pressure or appetite, and injection site irritation.
Can You Mix GHK-Cu with Hyaluronic Acid?
In a research setting, mixing GHK-Cu with hyaluronic acid is possible. This blend may potentially enhance skin hydration under experimental conditions.
What Are the Sources of GHK?
GHK is naturally found in human plasma and urine and is also synthesized for use in various lab studies and trials.
Why Buy GHK-cu Peptide from Sarmsamerica?
If you’re looking to buy GHK-Cu Peptides online, there are plenty of options available. However, not all companies selling GHK-Cu are trustworthy. It’s crucial to buy Peptides online only from reputable sources to ensure quality and reliability.
To buy GHK copper Peptides from a randomly selected website can be risky, even if the price seems reasonable, as you cannot be certain about their quality-control processes.
At Sarmsamerica, you can find the highest quality GHK-Cu for sale on the internet, with fast shipping. We are an American business headquartered in Wyoming, and our products are tested in U.S.-based third-party laboratories that certify a minimum of 98% purity. This rigorous testing ensures we offer the best GHK-Cu for sale on the market today.
Our research chemicals are lyophilized in glass vials and stored refrigerated to maintain potency. We operate a transparent business, avoiding discreet payment methods and ensuring no misrepresentation of our products. Explore the highest quality online.
For orders over $160, we offer free shipping. Need your items fast? We also provide express shipping services. Plus, sign up for our newsletter to get a 10% discount.
If you have any questions about our GHK copper Peptide or other products, please feel free to contact us, and we will respond as soon as possible.
References:
- Bissett, D. L. (2005). Anti-aging skin care formulations. In Cosmetic formulation of skin care products (pp. 191-210). CRC Press.
- Pickart, L., Vasquez-Soltero, J. M., & Margolina, A. (2015). GHK peptide as a natural modulator of multiple cellular pathways in skin regeneration. BioMed research international, 2015.
- Pickart, L., & Margolina, A. (2018). Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data. International journal of molecular sciences, 19(7), 1987.
- Pickart, L. (2008). The human tri-peptide GHK and tissue remodeling. Journal of Biomaterials Science, Polymer Edition,19(8), 969-988.
- Dou, Y., Lee, A., Zhu, L., Morton, J., & Ladiges, W. (2020). The potential of GHK as an anti-aging peptide.Aging pathobiology and therapeutics, 2(1), 58.
- Anastassakis, K. (2022). Copper Tripeptides Copper tripeptides. In Androgenetic Alopecia From A to Z: Vol. 2 Drugs, Herbs, Nutrition and Supplements (pp. 225-230). Cham: Springer International Publishing.
- Wang, X., Liu, B., Xu, Q., Sun, H., Shi, M., Wang, D., … & Feng, B. (2017). GHK‐Cu‐liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis. Wound repair and regeneration,25(2), 270-278.
- Zhao, R., Chen, Y., Ma, Y., Zou, C., Zhang, J., & Chen, Z. (2022). Innovation and transformation of chronic airway diseases. Frontiers in Molecular Biosciences,9, 1089813.
- Lau, S. J., & Sarkar, B. (1981). The interaction of copper (II) and glycyl-L-histidyl-L-lysine, a growth-modulating tripeptide from plasma. Biochemical Journal,199(3), 649-656.
- Pickart L, et al. The human tri-peptide GHK-Cu in prevention of oxidative stress and degenerative conditions of aging: implications for cognitive health. Oxidative Medicine and Cellular Longevity. 2012; 2012: 324832. doi: 10.1155/2012/324832.
Disclaimer: The GHK-Cu Copper Peptide Serum listed on this site is sold for research use only and is not intended for human consumption. This product is not a compound, supplement, food, or cosmetic, and should not be misused, sold, labeled, or branded as such.
