Description
Studies have highlighted numerous benefits of using IGF-1 LR3. For instance, one study demonstrated that IGF-1 LR3 supplemented muscle fibers in elderly rats, enhancing their strength, speed, and endurance. Researchers also suggest that IGF-1 LR3 can improve recovery time and stabilize muscle growth even without exercise. Sarmsamerica manufactures IGF-1 LR3 for sale, ensuring the highest quality and potency available on the market.
High Quality IGF1-LR3 for Sale Online
Insulin-like Growth Factor 1 Long R3 (IGF-1 LR3), also referred to as Long R3-IGF-1, is a synthetic analog of human IGF-1. IGF-1 is vital for regulating growth, development, and metabolism in the body. IGF-1 LR3 is engineered to have an extended half-life and greater potency than natural IGF-1, offering potential as a therapeutic agent for various conditions.
Key Features of IGF1 LR3
Structure and Composition:Â IGF-1 LR3 differs from natural IGF-1 in two significant ways:
- Arginine 3 (R3): The third amino acid in the IGF-1 LR3 sequence is arginine (R) instead of glutamic acid (E) in natural IGF-1. This substitution enhances IGF-1 LR3’s binding affinity to the IGF-1 receptor.
- N-terminal Extension:Â IGF-1 LR3 has an additional 13 amino acids at its N-terminus, which extends its half-life and reduces its binding affinity to IGF binding proteins (IGFBPs). IGFBPs regulate the availability and activity of IGF-1, and reduced binding to IGFBPs allows IGF-1 LR3 to remain active for a longer period.
Extended Half-life
IGF-1 LR3 has a half-life of approximately 16 hours, which is significantly longer than the estimated 10 minutes of natural IGF-1. This prolonged duration of action allows IGF-1 LR3 to exert its effects more effectively.
Mechanism of Action
IGF-1 LR3 is being explored for its potential therapeutic applications in various medical conditions:
- Muscle Wasting:Â IGF-1 LR3 may help treat muscle loss associated with aging, sarcopenia, and conditions like cancer cachexia.
- Growth Hormone Deficiency: IGF-1 LR3 could be used to boost IGF-1 levels in individuals with growth hormone deficiency.
- Wound Healing:Â IGF-1 LR3 may promote faster wound healing by enhancing cell proliferation and tissue regeneration.
Clinical Trials and Efficacy
IGF-1 LR3 is under investigation for its potential therapeutic applications in various medical conditions:
- Muscle Wasting:Â IGF-1 LR3 may help treat muscle loss due to aging, sarcopenia, and conditions like cancer cachexia.
- Growth Hormone Deficiency:Â IGF-1 LR3 could be used to boost IGF-1 levels in individuals with growth hormone deficiency.
- Wound Healing:Â IGF-1 LR3 may accelerate wound healing by stimulating cell proliferation and tissue regeneration.
Research finds of IGF-1 LR3
Studies on rats have shown numerous beneficial effects of IGF-1 LR3, including:
- Improved recovery time
- Enhanced physical performance
- Stable muscle growth, even without exercise
- Increased strength
- Prevention of age-related atrophy and loss of skeletal muscle function
Additionally, IGF-1 LR3 supplemented muscle fibers in elderly rats, restoring their strength, speed, and power to levels comparable to their younger years. These findings indicate potential for similar effects in human trials.
Data on our IGF1-LR3 For Sale
CAS Number: | 946870-92-4 |
Formula: | C400H625N111O115S9 |
Sequence: | MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA |
Molar Mass: | 9117.60 g/mol |
Half-life: | 20-30 Hours |
Class: | Polypeptide |
Storage: | Keep refrigerated upon reconstitution.
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IGF1-LR3Â FAQs
What is IGF-1 LR3 used for?
IGF-1 LR3 stimulates the production of growth hormone (GH), enabling users to replace fat with lean muscle, thereby enhancing muscle mass. IGF-1 LR3 offers significant potential for men and women seeking to transform their body appearance and improve their self-image.
Can IGF1 LR3 improve cognitive function?
Some studies indicate that IGF-1 LR3 may enhance cognitive function by increasing levels of brain-derived neurotrophic factor (BDNF). BDNF is a protein essential for the growth and survival of neurons, playing a crucial role in memory and learning. However, further research is needed to confirm the cognitive benefits of IGF-1 LR3.
How does IGF LR3 make you feel?
IGF-1 LR3 enhances energy levels and libido, helps alleviate feelings of depression, boosts cognitive function, and significantly increases muscle-building capabilities.
Can IGF1 LR3 help with wound healing?
IGF-1 LR3’s ability to stimulate cell proliferation and tissue regeneration may promote faster wound healing. Studies have demonstrated that IGF-1 LR3 can accelerate the healing process in various types of wounds, including skin ulcers and burns.
Is IGF1 LR3 found naturally in the body?
Yes, IGF-1 LR3 is a naturally occurring variant of IGF-1 produced in small amounts in the liver, kidneys, and other tissues. However, the synthetic form of IGF-1 LR3 is more potent and has a longer half-life than the natural version.
What are the future prospects for IGF1 LR3?
IGF-1 LR3 shows promise as a therapeutic agent for treating various conditions. However, more research is needed to confirm its safety and efficacy in humans.
If future studies yield positive results, IGF-1 LR3 could become a valuable treatment for muscle wasting, osteoporosis, diabetes, and other age-related conditions.
Why buy IGF1-LR3 from Sarms America?
When looking to buy IGF-1 LR3 online, there are numerous options available. However, buying Peptides from a randomly selected company can be risky.
Unfortunately, many companies selling Peptides do not conduct proper product testing or may conceal certificates and contact details for their third-party labs. This lack of transparency raises concerns about potential undisclosed information.
At Sarmsamerica, you can find the highest quality IGF-1 LR3 available on the internet. When you buy Peptides from Sarmsamerica, you are choosing top quality products.
Our IGF-1 LR3, acknowledged as the purest Peptide compound, undergoes rigorous testing and certification by accredited American third-party laboratories. These labs readily accept phone calls for certificate verification, ensuring transparency in our product quality.
Your IGF-1 LR3 will arrive in lyophilized form, securely packaged in glass vials, and refrigerated for stability. At Sports Technology Labs, transparency is paramount in every aspect of our operations, ensuring no need for discreet payment methods and guaranteeing precise product representation. We are dedicated to offering the utmost quality IGF-1 LR3 for online purchase.
We provide free shipping for orders over $160, along with expedited delivery options for those needing faster service. Sign up for our newsletter to receive a 10% discount on your purchase.
Opting for Sarmsamerica guarantees convenient access to premium IGF-1 LR3 online. Our steadfast dedication to reliable product standards, secure packaging, prompt delivery, and outstanding customer support distinguishes us from the rest.
For any questions regarding IGF-1 LR3 or our range of products, please contact us, and we’ll be happy to assist you promptly.
Scientific Research References:
- Bailes, J., & Soloviev, M. (2021). Insulin-like growth factor-1 (IGF-1) and its monitoring in medical diagnostic and in sports. Biomolecules, 11(2), 217.
- Ketha, H., & Singh, R. J. (2015). Clinical assays for quantitation of insulin-like-growth-factor-1 (IGF1). Methods, 81, 93-98.
- Yakar, S., Werner, H., & Rosen, C. J. (2018). 40 YEARS OF IGF1: Insulin-like growth factors: actions on the skeleton. Journal of molecular endocrinology, 61(1), T115-T137.
- Thornton, K. J., Kamanga-Sollo, E., White, M. E., & Dayton, W. R. (2016). Active g protein–coupled receptors (gpcr), matrix metalloproteinases 2/9 (mmp2/9), heparin-binding epidermal growth factor (hbegf), epidermal growth factor receptor (egfr), erbb2, and insulin-like growth factor 1 receptor (igf-1r) are necessary for trenbolone acetate–induced alterations in protein turnover rate of fused bovine satellite cell cultures. Journal of animal science, 94(6), 2332-2343.
- White, A., Stremming, J., Brown, L. D., & Rozance, P. J. (2023). Attenuated glucose-stimulated insulin secretion during an acute IGF-1 LR3 infusion into fetal sheep does not persist in isolated islets. Journal of Developmental Origins of Health and Disease, 14(3), 353-361.
- Chakravarthy, M. V. (2000). Modulation of replicative senescence of skeletal muscle satellite cells by insulin-like growth factor-I (IGF-I) (Doctoral dissertation, The University of Texas Graduate School of Biomedical Sciences at Houston).
- Sundgren, N. C., Giraud, G. D., Schultz, J. M., Lasarev, M. R., Stork, P. J., & Thornburg, K. L. (2003). Extracellular signal-regulated kinase and phosphoinositol-3 kinase mediate IGF-1 induced proliferation of fetal sheep cardiomyocytes.American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 285(6), R1481-R1489.
- Kyle, A. H., Baker, J. H., & Minchinton, A. I. (2012). Targeting quiescent tumor cells via oxygen and IGF-I supplementation. Cancer research, 72(3), 801-809.
- Yakar, S., & Adamo, M. L. (2012). Insulin-like growth factor 1 physiology: lessons from mouse models. Endocrinology and Metabolism Clinics, 41(2), 231-247.
- Miescher, I., Rieber, J., Calcagni, M., & Buschmann, J. (2023). In Vitro and In Vivo Effects of IGF-1 Delivery Strategies on Tendon Healing: A Review. International Journal of Molecular Sciences, 24(3), 2370.
- 11. Dyer, A. H., Vahdatpour, C., Sanfeliu, A., & Tropea, D. (2016). The role of Insulin-Like Growth Factor 1 (IGF-1) in brain development, maturation and neuroplasticity. Neuroscience, 325, 89-99.